For contact lens wearers there are two contact lenses most likely to hurt: your first pair of contact lenses and your last pair of contact lenses. The first pair is because of inexperience with inserting and removing contact lenses, and the latter may be due to something called contact lens overwear syndrome (CLOS). According to ...
source https://brintonvision.com/health-tips/contact-lens-overwear-syndrome/
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